What is Heparin Sodium?


Publish Time:

2021-02-03

Heparin sodium interferes with many stages of the blood coagulation process and has anticoagulant effects both in vivo and in vitro. Its mechanism of action is complex, mainly through binding to antithrombin III (AT-III), enhancing the latter's inhibitory effect on activated coagulation factors II, IX, X, XI, and XII. The consequences involve preventing platelet aggregation and destruction, hindering the formation of coagulation activators, preventing prothrombin from becoming thrombin, inhibiting thrombin, and thus preventing fibrinogen from becoming fibrin, thereby exerting its anticoagulant effect.

  Heparin sodium interferes with many stages of the blood coagulation process and has anticoagulant effects both in vivo and in vitro. Its mechanism of action is complex, primarily involving binding to antithrombin III (AT-III) to enhance the latter's inhibitory effect on activated coagulation factors II, IX, X, XI, and XII. The consequences include preventing platelet aggregation and disruption, hindering the formation of coagulation activators, preventing prothrombin from becoming thrombin, inhibiting thrombin, and thus preventing fibrinogen from becoming fibrin, thereby exerting its anticoagulant effect.